HORDB

ID: hor005336
Uniprot ID: P35808
Protein name: Adipokinetic hormone 2
Gene name: NA
Organism: Schistocerca gregaria (Desert locust) (Gryllus gregarius)
Family: AKH/HRTH/RPCH family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Schistocerca (genus), Cyrtacanthacridinae (subfamily), Acrididae (family), Acridoidea (superfamily), Acridomorpha, Acrididea (infraorder), Caelifera (suborder), Orthoptera (order), Polyneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway; GO:0007629 flight behavior
GO CC: GO:0005576 extracellular region

Function: causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005336_AF2.pdb

hor005336_ESM.pdb

Mass:	107707	Formula:	C44H61N11O13
Absent amino acids:	ACDEHIKMPRVY	Common amino acids:	FGLNQSTW
pI:	6.11	Basic residues:	0
Polar residues:	4	Hydrophobic residues:	3
Hydrophobicity:	-40	Boman Index:	-698
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	48.75
Instability Index:	-522.5	Extinction Coefficient cystines:	5500
Absorbance 280nm:	785.71